The US, early on Thursday, launched a second wave of attacks on Iran’s coastal defences and missile sites within a span of 24 hours after reimposing a naval blockade of Iranian ports, and Tehran responded by again targeting US military sites in neighboring Gulf countries.

The latest escalation comes days after a fragile truce collapsed, raising the specter of a return to full-scale war, with Iran once again threatening to shut off more regional energy exports after blocking the vital Strait of Hormuz.

Hostilities have intensified since Iran said late on Saturday it had closed the Strait of Hormuz. Military operations are also keeping ships from transiting the vital artery, which carried about a fifth of global oil and gas shipments before the US-Israeli war on Iran.

Brent crude oil, the international benchmark, closed at a one-month high of $84.95 a barrel on Wednesday.

US Central Command said the military had attacked coastal defence systems and cruise missile storage and launch sites on Iran’s Greater Tunb Island starting around 6am EDT, then launched a second wave of strikes against multiple cities nine hours later.

“US forces struck Iranian command centres, air defence sites, missile and drone capabilities, and coastal surveillance facilities,” it said in a statement, adding it also hit targets in Bandar Abbas, home to Iran’s largest port and key navy and Iran’s Revolutionary Guards facilities on the Strait of Hormuz.

“Earlier this morning, American forces struck coastal defence and cruise missile sites on Greater Tunb Island during a 90-minute wave,” the US military added.

The US military also said it disabled an unladen oil tanker attempting to sail toward Iran’s Kharg Island after it ignored multiple warnings, firing Hellfire missiles into the ship’s smokestack. Since resuming a naval blockade against Iran on Tuesday, the US has redirected two ships and disabled another, the military said.

Iranian news media reported a series of explosions, mainly in coastal areas such as Bandar Abbas. Other explosions or projectile strikes were reported around the city of Ahvaz, just inland from the northern end of the Gulf, and Konarak, Sirik and Qeshm in southern Iran.

Press TV reported at least two explosions in the central Iranian city of Khondab, about 250 km southwest of Tehran. Mehr news agency reported Iran activated its air defences in Tehran to counter “hostile threats.”

Iranian state broadcaster IRIB reported that the US attacks struck near a hospital in Ahvaz that houses a pediatric cancer centre, forcing the temporary evacuation of the hospital. Families have come out to the streets around the hospital to care for their children, IRIB said.

For its part, the Islamic Revolutionary Guard Corps (IRGC) said it had struck US military targets in the region, including in Bahrain, Kuwait and Jordan.

The Guards said it targeted the “communication systems and fuel storage facilities of the US military” in Jordan.

Separately, the IRGC said it struck “radar systems, a Patriot air defence system, and fuel storage facilities at Ali Al Salem Air Base” in Kuwait and US military facilities at the Sheikh Isa Air Base in Bahrain, IRIB reported.

The war has killed thousands of people and displaced millions, mainly in Iran and Lebanon, where the conflict restarted between Israel and Hezbollah.

After the first wave, Tehran’s top negotiator Mohammad Baqer Ghalibaf issued a statement declaring that Iranian security depended on maintaining what he called “Iranian arrangements” in the strait.

“We are in an essential and existential war with America,” Qalibaf said.

Trump claims Iran wants to settle

US President Donald Trump struck a triumphant note, as he has repeatedly since the US and Israel started hostilities on February 28, saying, “We’ll have Iran defeated soon. They’ll be defeated very soon.”

Speaking at a roundtable event at the Pennsylvania Defence and Innovation Summit, Trump also claimed the Iranians want to “settle so badly”.

“They don’t like what we’re doing, and they do want to settle. We’ll find out whether or not we settle with them, or we just finish it off,” Trump said.

On Tuesday, Trump said US negotiators had been in touch with their Iranian counterparts to tell them “you better make a deal.”

Iran’s military spokesperson said that the only way to reopen the Strait of Hormuz was for the US to comply with the 14-point memorandum of understanding that the two sides signed in June, and the implementation of “Iranian regulations” regarding ship traffic in the strait.

Even amid the hostilities, there was a possible sign of goodwill. Trump said Iran had allowed an American who was “wrongfully detained” during the Biden administration’s tenure in 2024 to leave the country.

“The United States of America appreciates this gesture of Goodwill by Iran,” Trump wrote on Truth Social.

Human rights attorney Jared Genser identified the released American as Dena Karari, who had been prevented from leaving Iran since December 2024.

“Dena is now safe and traveling back to the United States,” Genser wrote on X, thanking Trump for his efforts to free her.